MUNICH — Patients with heart failure who are treated with digoxin administered according to the standard nomogram risk getting an overdose that might kill them.
“We recommend treating patients who get digoxin with half the dose from the nomogr…
Concepts in clinical pharmacokinetics, 4th ed.
Ed. by Joseph T. DiPiro et al.
Am.Soc./Health-Sys.Pharmacists
2005
230 pages
$99.00
Paperback
RM301
The 15 lessons in this pharmacy textbook define the time course of drug absorption and metabolism in the human body, examine the relationship between drug concentration at the site of action and the resulting effect, …
VANCOUVER, B.C. — The latest Cochrane systematic review of digoxin for treatment of heart failure patients in sinus rhythm paints a picture of a more than 200-year-old drug that’s still clinically useful, although it has no effect on mortality, William B. Hood Jr., M.D., said at a meeting sponsored b…
Digoxin appears to raise the risk of death in stable heart failure, but only in women, according a post hoc analysis of data from a clinical trial.
This finding is based on “robust evidence” and “provides sufficient grounds for a reexamination of the use of digoxin therapy for women with heart failure,” said Saif S. Rathore, a public health specialist at Yale …
To the Editor: Acute mesenteric ischemia occurs in 1 of 1000 hospital admissions, and a nonocclusive mechanism makes up about 20% of these cases. (1) Nonocclusive mesenteric ischemia (NOMI) is a condition where the macrovasculature is patent, but the microvascular blood flow is inadequate to meet intestinal tissue demands leading to gangrene and disastrous consequenc…
